| New data model reveals new recommendations for infertility treatment | | A new data analysis model developed in part by University of Minnesota faculty is shedding more light on potential treatment for women facing infertility issues, offering possibilities for the future of health recommendation tools. |
In a study recently published in the Journal of the American Statistical Association , Carlson School of Management assistant professor Xuan Bi and colleagues examine existing data on 1376 women with polycystic ovary syndrome (PCOS). The condition is one of the most common causes of infertility, but it is not well understood. Why? The data set is reduced.
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| | What advances does the new year hold in the field of infertility? | | The fight against the clock to ensure maternity, making up for time lost due to the pandemic, will be one of the great challenges for fertility clinics. A study, published by the journal Reproductive Biomedicine Online, analyzes the effects of Covid-19 mitigation measures on fertility and infertility management practices by different clinics and concludes that most infertility treatments were delayed during the pandemic. Conducted among leading clinics in 43 countries in Asia (13), Africa (3), Europe (17), North America (3), Oceania (2) and South America (5), the study, written by a group of Australian researchers, insists on the need to update treatments, stopped by Covid-19. | | Tags: Investigation - View source
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| Cannabis affects sperm count and motility in two generations of mice | | Intense but short-term exposure to cannabis vapor lowered sperm count and slowed sperm movement or motility, not only in directly exposed male mice, but also in their offspring, according to a new study. The findings are based on other research in humans and animals, showing that cannabis can impair male reproductive function. The current study uses more controlled circumstances than human studies, which often have to rely on surveys, and is the first known reproductive study to use vaporized whole cannabis in mice, which is the most common form used by humans. Previous animal studies use other methods of administration such as injections of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. | | Tags: Investigation - View source
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| | Severely obese women are 50% less likely to become pregnant | | The Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Society for the Study of Obesity (SEEDO), together with the Spanish Association of Urology (AEU) and the Spanish Fertility Society (SEF) come together to commemorate the Day of the fight against obesity with the motto: 'Infertility, a compelling reason', since this disease, obesity, is also the cause of other lesser known diseases, such as infertility. Their representatives have given some data such as that almost 40% of adults in Spain are overweight and, in addition, it affects their fertility; Severely obese women are 50% less likely to become pregnant, and up to 60% of obese men may suffer from erectile dysfunction. And 20% of them have decreased fertility. | | Tags: Investigation - View source
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| Smoking during pregnancy can harm future pregnancies | | Researchers have found that the link between smoking early in pregnancy and having a smaller baby can extend to future pregnancies. Researchers in Southampton have found that the link between smoking early in pregnancy and having a smaller baby can extend to future pregnancies. The findings showed that women who smoked early in their first pregnancy were more likely to have a smaller than expected baby in their second pregnancy compared to nonsmokers. This was even the case where they reported that they stopped smoking early in their second pregnancy. | | Tags: Investigation - View source
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| | Scientists develop sperm from primate stem cells | | A new study shows that functional sperm can be produced in a dish using primate embryonic stem cells. The researchers used embryonic stem cells from rhesus macaque monkeys to generate immature sperm known as round spermatids, which were shown to be capable of fertilizing a rhesus macaque egg. | | Tags: Investigation - View source
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| Births grow 1,3% through In Vitro Fertilization and Artificial Insemination treatments | | The Ministry of Health and the Spanish Fertility Society (SEF) have presented the latest data from the National Activity Registry, referring to the year 2019. The number of births through In Vitro Fertilization and Artificial Insemination treatments has increased by 1,3% , but with fewer procedures, 0,6%, which is interpreted as an improvement in the quality of the techniques and the results. | | Tags: Treatments - View source
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| | New test quickly detects bacteria associated with increased risk of preterm birth | | A study has found that a new device can quickly and accurately detect changes in vaginal bacteria and corresponding immune responses in pregnant women. These changes are associated with an increased risk of preterm birth. The test could help identify women at risk for preterm labor earlier, which could allow obstetricians to monitor these women more closely and begin preventive treatments earlier and in a more targeted way than is currently possible. |
This is according to researchers at the March of Dimes Prematurity Research Center at Imperial College London, who have published their work in Nature Communications.
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| Choosing the best embryo in In Vitro Fertilization | | Each year, tens of thousands of babies are born in the United States as a result of IVF (in vitro fertilization), where several eggs are fertilized outside of the mother's body and then an embryo is selected for transfer to her uterus. For several years, future parents have been able to screen their embryos for rare genetic defects such as cystic fibrosis or Tay-Sachs disease. |
However, new technical advances now make it possible for parents to test their embryos for genetic risk factors for diseases such as cancer, diabetes, heart disease, or psychiatric disorders such as schizophrenia.
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| | Pregnant women with symptomatic COVID-19 are more likely to have emergency deliveries | | Pregnant women with symptomatic COVID-19 had a higher percentage of emergency complications compared to asymptomatic COVID-19 pregnant women, and newborns of symptomatic mothers were more likely to require supportive oxygen and admission to the intensive care unit neonatal patients (NICU), according to a study presented at the ANESTHESIOLOGY 2021 annual meeting. | | Tags: Investigation - View source
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| Our brain takes shape during the middle of pregnancy | | About four to five months after conception, a burst of synaptic growth begins in the prefrontal cortex (PFC) of the human fetus. And within this tangled mass of connections, the developing brain takes on the unique properties that make humans capable of abstract thinking, language, and complex social interactions. | | Tags: Investigation - View source
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| | USPSTF recommends aspirin for people at high risk of preeclampsia | | The US Preventive Services Task Force (USPSTF) recommends low-dose aspirin to reduce the risk of pre-eclampsia among people at high risk. This recommendation forms the basis of the final recommendation statement published in the September 28 issue of the Journal of the American Medical Association. |
Jillian T. Henderson, Ph.D., MPH, of the Kaiser Permanente Evidence-based Practice Center in Portland, Oregon, and colleagues conducted a systematic review to update the USPSTF evidence on the effectiveness of aspirin in preventing Preeclampsia in individuals at increased risk based on clinical risk factors or measurements. We included data from 23 randomized clinical trials with 26952 participants, including 18 trials among participants at increased risk of pre-eclampsia. The researchers found that the incidence of pre-eclampsia ranged from 4 to 30 percent in the trials of participants at higher risk. Aspirin use was significantly associated with lower risks of preeclampsia, perinatal mortality, and preterm delivery, and intrauterine growth restriction (combined relative risks, 0,85, 0,79, 0,80, and 0,82, respectively). There was no significant association of aspirin use with the risk of postpartum haemorrhage or other haemorrhage-related harm.
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| A common antibiotic reduces low birth weight and prematurity | | According to research, a common antibiotic has been found to reduce low birth weight and premature births, if taken during pregnancy, in countries where malaria is endemic. |
The researchers reviewed 14 studies conducted in African and Asian countries, involving 17.594. The systematic review, led by the Murdoch Children's Research Institute (MCRI) and published in The Lancet EClinicalMedicine, found that the antibiotic azithromycin reduced underweight when birth and prematurity in Africa and Asia, but it did not reduce infant deaths, infections and hospital admissions.
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| | Treat infertility with drug-releasing microspheres | | For an embryo to survive, it must adhere to the lining of the uterus within a few days of conception. However, if this lining, called the endometrium, is too thin, the embryo cannot latch on. Now, researchers reporting in ACS Biomaterials Science & Engineering have developed a new system aimed at treating infertility in women with thin endometria. Its tiny microscale particles stimulated the growth of blood vessels, producing promising results in preliminary experiments in cells and mice. |
Poor blood flow within the endometrium limits its thickness, and researchers have struggled to find an effective way to stimulate the formation of new blood vessels. Some have begun to explore the use of microspheres to deliver treatment. However, current methods for manufacturing these small particles face challenges, including the need for complex and demanding production methods and too much variation in the sizes of the spheres. So Xiangguo Wang, Lei Yang, and their colleagues wanted to devise a simple and efficient technique to fabricate uniform microspheres charged with a compound known to be a powerful stimulator of the crecimiento of blood vessels.
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| Are the "Unborn" most common in women infected with COVID? | | COVID-19 is on the rise in US states with low vaccination rates, and these places may also be experiencing a higher than usual number of "Unborn" related to the virus. |
While the "Unborn" number, Still very low nationally, doctors in the Deep South have noted increases in stillbirths, NBC News reported. One of those states is Alabama. But the numbers are too low overall to draw definitive conclusions about whether COVID cases led to an increase in stillbirths, said Dr. Akila Subramaniam, associate professor in the Division of Maternal-Fetal Medicine at the University of Alabama at Birmingham.
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| | Reception of Covid-19 mRNA vaccines and risk of miscarriage | | Pregnant people are at risk for severe coronavirus disease 2019 (Covid-19), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy is associated with an increased risk of childbirth. premature and other adverse maternal and neonatal outcomes. |
Although miscarriage (pregnancy loss that occurs before 20 weeks of gestation) is a common pregnancy outcome affecting 11 to 22% of recognized pregnancies. Data to report estimates of the risk of miscarriage after receiving a Covid-19 mRNA vaccine before conception (30 days before the first day of the last menstrual period up to 14 days after) or during pregnancy are limited.
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| New discovery signals 'golden window' for IVF success | | Researchers find a way to better identify the 'golden window' when a uterus is ready for pregnancy, in a discovery that could help increase IVF success rates. |
Researchers have found a way to better identify the "golden window" when a uterus is ready for pregnancy, in a discovery that could help increase IVF success rates.
The team found that levels of this molecule on the surface of the uterus decrease at a certain point in the menstrual cycle.
This allows the uterus to become stickier, opening the "golden window" for successful pregnancy.
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| | Pregnant women do well with the COVID vaccine | | A survey of more than 17,000 pregnant and lactating women who received the COVID-19 vaccine showed that they did not experience more severe symptoms than their non-pregnant counterparts. |
The UW Medicine study, published today in JAMA Network Open, showed that "there was no increase in reactions in pregnant women beyond what is expected from a vaccine," said Dr. Linda Eckert, professor of obstetrics and gynecology at the School of the University of Washington. of Medicine and lead author of the study. The findings come a week after the Centers for Disease Control and Prevention formally recommended that all pregnant women get vaccinated against the virus. The CDC reported that only 23% of pregnant women in the US were vaccinated at the end of July. The percentage is even lower among women of color and Latinas.
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| Exposure to prenatal antipsychotics seems safe | | Exposure to prenatal antipsychotics does not appear to be associated with an increased risk of attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), or small for gestational age, according to a study published online Aug. 1. . 16 in Internal Medicine JAMA. | | Tags: Investigation - View source
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| | From 2011 to 2019, gestational diabetes rates increased in all races and ethnicities. | | From 2011 to 2019, rates of gestational diabetes increased in all racial and ethnic subgroups and across all ages, according to a study published in the Aug. 17 issue of the Journal of the American Medical Association. |
Nilay S. Shah, MD, MPH, of Northwestern University Feinberg School of Medicine in Chicago, and colleagues used data from the National Center for Health Statistics for 12,610,235 people aged 15 to 44 years with first single live births from 2011 to 2019. XNUMX in the United States to examine whether the rates of diabetes gestational have changed.
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| Vaping during pregnancy is harmful to offspring into adulthood | | The use of electronic cigarettes ("vaping") during pregnancy represents a significant risk to the health of the offspring, since it affects the function of blood vessels even in adulthood, according to a new study by researchers from the Faculty of West Virginia University (WVU) Medicine |
The diminished capacity of the blood vessels increases the risk of stroke, heart attack and other cardiovascular problems. This study was conducted using a rat model. Female rats were exposed to e-cigarette aerosol for one hour a day for five days a week during pregnancy. The pups were examined at XNUMX, XNUMX and XNUMX months (adulthood), at which point the adverse effects of vaping were discovered.
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| | The progress of IVF embryos responds positively to mechanical activation | | A recent article, published by a group of scientists from India, Greece and the United Kingdom, in the prestigious Cochrane Revies Library, summarizes different activation methods including the Tesarik technique, which they consider to be the potentially least dangerous and simplest. This technique allows solving the cases in which the eggs injected with sperm that do not become embryos of couples who choose in vitro fertilization through ICSI. | | Tags: Investigation
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| Two Emerging Trends in Treatment Explain Steady Increase in IVF Success Rates | | A large cohort study from the Swedish national IVF registry, which included nearly 125.000 treatments carried out between 2007 and 2017, has concluded that the steady rise in birth rates can be attributed to two emerging clinical trends in IVF: embryo transfer at the blastocyst stage of development and the increasing use of embryo freezing (with quick freeze vitrification technology). | | Tags: Investigation - View source
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| Female embryos develop earlier than male embryos | | The results of a study of 102 embryos have certified that the processes between the cavitation and blastocyst phases have different rhythms between the sexes. Eugin Laboratories has coordinated an investigation in which a series of patterns have been identified according to which female embryos would develop faster than male embryos. According to experts, the most significant difference lies in a phase of the embryonic process in which the difference between the sexes was detected. | | Tags: Investigation - View source
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| | Alcohol reduces the chances of pregnancy | | Drinking alcohol is linked to lower chances of pregnancy according to a study. The associations between alcohol consumption and the chances of getting pregnant suggest that women who want to conceive should avoid heavy drinking. In the second half of the menstrual cycle, even moderate alcohol consumption is linked to lower chances of pregnancy. | | Tags: Investigation - View source
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| Drinking alcohol is linked to lower chances of pregnancy | | A study of the associations between alcohol consumption and the chances of getting pregnant suggests that women who want to conceive should avoid heavy drinking. In the second half of the menstrual cycle, even moderate alcohol consumption is linked to lower chances of pregnancy. | | Tags: Investigation - View source
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| Genetic link to male infertility is identified | | Researchers have discovered a genetic variant linked to male infertility, which could improve the diagnosis and management of men who carry it. Scientists from the Wellcome Sanger Institute and the University of Tartu conducted the largest genetic study to date examining unexplained infertility in men and finding a common Y chromosome subtype that increases the risk of fertility problems for the carrier in a substantial proportion of men of European descent | | Tags: Investigation - View source
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| Pregnant women immune to COVID vaccines, transmit antibodies to newborns | | In the largest study of its kind to date, researchers at Massachusetts General Hospital, Brigham and Women's Hospital, and the Ragon Institute at MGH, MIT, and Harvard have found that new COVID-19 mRNA vaccines are highly effective at producing antibodies against SARS. CoV-2 virus in pregnant and lactating women. They also showed that vaccines confer protective immunity to newborns through breast milk and the placenta. | | Tags: Investigation - View source
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| | Automated Embryo Selection System Could Increase Infertility Treatment Success | | The team of researchers from Kaunas University of Technology (KTU), Lithuania, applied artificial intelligence (AI) methods to evaluate human embryo development data. The AI-based system photographs the embryos every five minutes, processes their developmental data, and reports any observed abnormalities. This increases the likelihood of choosing the most viable and healthy early-stage embryo for IVF procedures. The innovation was developed in collaboration with Esco Medical Technologies, a manufacturer of medical equipment. | | Tags: Investigation - View source
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| | Endometriosis is more common in young women than many doctors think | | Medical experts are not sure what causes endometriosis, but there are many possibilities, including retrograde menstrual flow (when endometrial tissue sheds during a woman's period and inadvertently passes through the fallopian tube to other parts of the body ), genetic factors and problems. | | Tags: Treatments - View source
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| When is it advisable to freeze all embryos in in vitro fertilization? | | An article recently published in the Journal of Gynecology and Women 'Health by scientists from the MARGen clinic in Granada reviews the arguments for and against freezing all embryos, from the point of view of safety for the mother and the mother. of the probability of achieving a pregnancy with the transfer of fresh embryos or with frozen embryos. |
Many women with a strong response to ovarian stimulation run a high health risk if they become pregnant in the same attempt. This can be avoided by giving up the immediate transfer of the embryos resulting from stimulation and postponing this intervention until later, when the transfer can be performed without ovarian stimulation, using previously frozen embryos.
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| | IUD saves fertility in women with cancer | | A common intrauterine device (IUD) could help preserve fertility and reduce the need for hysterectomies in women with endometrial cancer, according to research from the University of Queensland. | | Tags: Investigation - View source
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| | Endocrine disruptors threaten semen quality | | A growing number of studies show that environmental factors and the lifestyle of pregnant women play an important role in the health of their children. But what about the quality of young men's semen? | | Tags: Investigation - View source
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| The bioprosthetic ovary | | Progress towards the development of 'ink' for 3D printing of a bioprosthetic ovary. A giant step forward in fertility preservation and hormonal restoration | | Tags: Investigation - View source
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| | Premature birth could be predicted 10 weeks after conception | | Mothers at risk for preterm labor could be identified much earlier in pregnancy than current tests allow by looking for specific bacteria and chemicals in their cervicovaginal fluid. |
The new study, published in the Journal of Clinical Investigation by researchers from King's and the pregnancy charity Tommy's, discusses how clues into the mothers vaginal microbiome (small living organisms that can affect health, such as bacteria and viruses) and metabolome (small molecules naturally created by the body , such as sugars and acids) can help predict the risk of premature birth .
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